Silicon Valley’s Billionaires Seek to Hack Aging Process by Reprogramming Human Cells

(MIT Technology Review) — Last October, a large group of scientists made their way to Yuri Milner’s super-mansion in the Los Altos Hills above Palo Alto. They were tested for covid-19 and wore masks as they assembled in a theater on the property for a two-day scientific conference. Others joined by teleconference. The topic: how biotechnology might be used to make people younger.

Milner is a Russian-born billionaire who made a fortune on Facebook and Mail.ru and previously started the glitzy black-tie Breakthrough Prizes, $3 million awards given each year to outstanding physicists, biologists, and mathematicians. But Milner’s enthusiasm for science was taking a provocative and specific new direction. As the scientific sessions progressed, experts took the stage to describe radical attempts at “rejuvenating” animals.

That meeting has now led to the formation of an ambitious new anti-aging company called Altos Labs, according to people familiar with the plans. Altos is pursuing biological reprogramming technology, a way to rejuvenate cells in the lab that some scientists think could be extended to revitalize entire animal bodies, ultimately prolonging human life.

The new company, incorporated in the US and in the UK earlier this year, will establish several institutes in places including the Bay Area, San Diego, Cambridge, UK and Japan, and is recruiting a large cadre of university scientists with lavish salaries and the promise that they can pursue unfettered blue-sky research on how cells age and how to reverse that process.

Some people briefed by the company have been told that its investors include Jeff Bezos, the world’s richest person, who stepped down as CEO of Amazon in July and weeks later risked his life by jumping into a rocket capsule to reach outer space. Technology Review confirmed that Milner and his wife Julia have invested in Altos through a foundation.

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